Blog Image

The ISBGroup Blog

About the blog

Here you can read about everything that's happening in the ISB Group.

28th of April: A Biomedical Engineering conference at Linköping University

Events Posted on Tue, April 12, 2022 07:00:00

The Biomedical Engineering conference at Linköping University BME@LiU 2022 is a day filled with activities related to the field of Biomedical Engineering. The conference reaches out to researchers, companies, and organizations, who support, contribute to, or utilize Biomedical Engineering Technologies. This involves development of state-of-the-art technologies such as biosensors, medical imaging, AI, eHealth, visualization, with many applications in Life Sciences, e.g., circulatory and metabolic diseases, inflammation, neurological diseases and cancer.

BME@LiU 2022 will offer several levels of engagement: invited and contributed talks, posters, exhibitions, mingling arenas, and a dinner.


When? April 28, 08.00 – 17.00

Where? Campus US at LiU and online

Last date to register: April 14 2022. To register, click here

More information about the conference can be found here.


Keynote speakers:

Torbjörn Kronander, CEO Sectra

Jessica C. Ramella-Roman, Dr/Associate professor at the Medical Photonics Laboratory

Lena Miranda, CEO Linköping Science Park

Gerhard Andersson, Professor at the Department of Behavioural Sciences and Learning (IBL)

Uncategorised Posted on Mon, June 14, 2021 11:36:20

Nu är programmet för Almedalen ute, och vi kommer att dyka upp i diskussioner kring den Digitala Tvillingen på måndag den 5 juli kl 13.15-14.00. Missa inte! Konferensen är digital så du kan se den bekvämt hemifrån soffan.

Programmer wanted!

Uncategorised Posted on Tue, May 25, 2021 11:30:31

We are looking for a programmer to work on the interface for the digital twin project. Please spread to anyone you think would be a good match!

Ansök här / Apply here

Here is a short film about the Digital Twin project.

Our work with the new digital twin technology – an interactive computer model, describing the multi-organ, and multi-timescale biochemistry and physiology of a specific person – has now led to a first prototype which is almost ready to be tested in a clinical environment. However, to be able to do that, we need to have suitable user interface, and this is where you come in!

In english:

“We are looking for someone experienced in working with programming, visualisation, software architecture, and user friendliness. Submitting a sample of previous work with you application will increase your chances, in particular apps and software projects that includes visualisation. You are interested in design and you are an attentive listener who can work in a group setting to interpret the best solution to what researchers, clinical personnel and private users need.

Your tasks will primarily be development of the front-end software for research and clinical environments, focusing on visualisation and app-design. ISB group at IMT have developed a so called Digital Twin, computer model copies of a patient, which will function as support for the Health Conversation. We have a few previously developed prototypes, but now we need someone to help us make a version with a user interface suitable for testing in clinical studies. You will work mostly with the coding of the software, but some design and user interaction and evaluation is also included.”

På svenska:

“Vi söker nu någon som har erfarenhet av att arbeta med programmering, visualisering, mjukvaruarkitetktur och användarvänlighet.  Tidigare arbetsprov av egna utvecklade appar och andra mjukvaruprojekt, speciellt sådana som inkluderar en visualiseringskomponent, är en viktig del av bedömningen. Du är antagligen intresserad av design och en god lyssnare som kan arbeta i grupp och tolka vad både forskare, vårdpersonal och privata användare behöver. 

Dina arbetsuppgifter kommer bestå i framför allt arbete med att utveckla front-end mjukvara för en vetenskaplig och klinisk miljö, med fokus på visualisering och app-design. I ISB-group på IMT har vi utvecklat en så kallad Digital Tvilling, datorkopior av en patient, som ska fungera som stöd i vårdens hälsosamtal. Vi har tidigare utvecklat ett par prototyper, men behöver nu någon som gör en första mer färdig version av användargränssnittet att testa i kliniska studier.  Du kommer att arbeta mycket med själva kodningen av mjukvaran, men en del design och användarinteraktion ingår också. “

If you have any questions, please contact Karin Lundengård at

New students!

Uncategorised Posted on Tue, April 14, 2020 14:02:36

We have several master-thesis and internship students working in our group this spring. Here is a small introduction!

Gustav Magnusson

I’m a master student in Physics with a hope to contribute something to the world of Systems Biology. The aim of my master thesis is to work with the Digital Twin, to put together the various models produced here at ISB to form an interface for users such as patient and researchers to test various situations and hypothesis. The goal is also to work on my own model which could be a part of the Digital Twin, perhaps with focus towards phyisical training, atherosclerosis or the immune system.

Lucas Raihle
Hi! I’m Lucas and I will be interning at ISB group during March-September. My project will revolve around making a model that can describe how diet affects the progression of NAFLD (non-alcoholic fatty liver disease). NAFLD is the most common liver disease in the world and is heavily correlated with the metabolic syndrome. Understanding the progression of NAFLD could lead to more effective forms of treatment and diagnosing. I’m happy to join this group and excited to start my project.

Johanna Hansson
Hi, my name is Johanna Hansson and I have just started an internship at ISB group. I will be working on a project to describe the disease progression of atherosclerosis to stroke and how the consequential oxygen loss affects the brain function. First, I will develop a mechanistic atherosclerosis model and later connect it with existing models of e.g. blood flow and stroke. Understanding atherosclerosis and its relationship with stroke could help predict who is at risk of having one. With that knowledge, we may be able to prevent the stroke from happening and save lives. I will work on my project for 6 months and I am excited to see the result!

Jonatan Baggman
Hi! My name is Jonatan and I’m doing my master thesis here at ISB group this spring. For my master thesis I’m looking into imputations for the Digital Twin, how to estimate the input values which are not measured directly from the patient. I will look into different methods of imputation and will compare these. Hopefully, I will be able to present how to make the Digital Twin personalized without measuring all values from the patient!

Seminar day on non-animal perspectives in biomedicine and drug development with 3R

3R and animal experiments, Events, Systems biology and science Posted on Tue, January 14, 2020 19:28:05

Today, parts of the group participated at a seminar day with the Swedish 3R center in stockholm, both with posters, presentations and in discussions.

The day consisted of presentations from people doing research that can/could lead to replacement of animal testing – specifically on organs on a chip and mathematical modelling – and a panel discussions. In the panel discussions, among other things, the capabilities of the presented research to replace animal testing was discussed, what they can replace, and what the hurdels of making that happen are. All in all, the day gave a clearer vision on where we are, where we couldget, and how to do it.

From the panel discussion. From left to right, Per Artursson, Uppsala University, Karin Stenkula, Lund University, Lotte Martoft, AstraZeneca, Peter Gennemark, AstraZeneca, and Gunnar Cedersund chairing the discussions.

More grants to Systems Biology in Linköping

Uncategorised Posted on Thu, November 28, 2019 16:36:06

Elin has received two substantial grants, from the Swedish Research Council (VR) and from the Center for Industrial Information Technology (CENIIT). Both grants are given to young and promising researchers.

VR-NT From omics to patient specific simulations (950 000 SEK per year for 4 years)
CENIIT Executable models for drug development (450 000 SEK per year for up to 6 years)

Precise4Q meeting in Linköping

Events, News Posted on Tue, November 12, 2019 16:02:17

During 7th and 8th of the November, we have had meeting with our partners in the PRECISE4Q project here in Linköping. In PRECISE4Q, we are working wit developing hybrid models for a decision support for Stroke treatment together with scientists within health informatics, computer science, machine learning, medicine, etc.

During the meetings, we discussed our upcoming EU review (we are financed by EUs Horizon 2020 project), how we should move forward in general, and met with local scientists here in Linköping that are working with similar things.

Master thesis presentation

Uncategorised Posted on Fri, October 04, 2019 18:18:09

Today, Therese Alenvret presented here master thesis on how health information from the clinic and/or different mobile devices can be retrieved and modeled to be used by our digital twin. So now we now more about the posibilities and challanges with accessing personal data to the digital twin. Good job Therese!

« PreviousNext »