The ISBGroup Blog

Hello,

My name is Jonna and I am a Dutch student doing my
internship at the ISB group. I will be staying in Sweden to work on this
project for 3 months. Back home I am a master student in the Medical
Engineering program of Eindhoven Universtity of Technology. This externship is
the final part of my master studies.

Previously I have done most of my projects on
bioinformatics/data analysis so I am very excited to learn more about the
systems biology modeling techniques. This project is a great opportunity to
gain more modeling experience. During my
time here I will be working on modeling the liver.

In my free time I like to swim and explore the city/area a
bit since I am new in town. I’ve spent many of my holidays in Scandinavia (mostly
Sweden) so I am very happy to be living here for a few months. I have had a
part-time job in a swimming pool where I received my first aid certificate,
which I used my first morning in Linköping during helping a patient in the
street after a traffic accident in the city center. So my time in Sweden
started out quit hectic, hopefully that is not a precursor to how the coming
months will be.

I am looking forward to meeting all group members and working
on the project within the ISB group.

Hello!

My name is Anton Tornerefelt, I’ve just finished my third
year studying engineering biology.

Having recently finished my Bachelor’s project, which
sparked my interest in systems biology and modeling, I was eager to continue
working on this topic. Thankfully, I was granted the opportunity to work with
the ISB group for almost a year. My work will be focused on the different effects of
T-cell differentiation.

When I am not working, I enjoy wasting my time on watching movies and occasionally jogging.

I am looking forward to work and to bond with all colleagues here at the ISB-group!

Hi, my name
is Henrik, I’ve been accepted to the research preparation course (the
internship).

The subject of the internship is not completely decided yet, but it will involve the connection
between a brain function and the blood circulation.

Up until
now I’ve finished my bachelor project and with that my 3rd year at
the Engineering Biology program.

I am an
active person and like to train, previously I’ve been doing sports (mainly
swimming), and I spend a lot of my time at the gym.

I am looking forward to my time with the ISB group and am hoping for a fun and a instructive period.

Last week some of us (Gunnar, William, Christian, Fredrik and Thea) went to Gothenburg to attend the Second Swedish Diabetes Summit. It’s a summit bringing together basic and clinical research.

We had a good time listening to some really interesting presentations with topics varying from treatment of metabolic diseases to artificial intelligence in health and diabetes. Gunnar was chairman for the session of AI and he and William also presented a poster each.

/Thea

This
autumn, we welcome another new student in our group: Josef Grännö

Hello, my name is Josef, I study medicine, and
I’m here at ISB Group to do a project for my 6th semester.

My project is about glycemic management in
patients admitted to the intensive care unit. During my time here I will
compare different models that aim to be used as decision support systems to
help ICU staff maintain the patient’s glucose levels in optimal range. I
collaborate mainly with the GlucoSafe group that is based in Aarhus, Denmark.

When not desperately trying to understand
mathematics I enjoy the outdoors, volleyball and amateur acting.

This autumn, we welcome another new student in our group: Christian Simonsson

Hi!

My name is
Christian Simonsson and I will be doing my master thesis here in the ISB-group.
I am a 5th year engineering biology student with my master’s profile
being Materials and Sensors in Biomedince. For my master’s thesis I wanted to
do something a bit different from what I have been doing the last two years. Since
my Bachelor’s project was on the topic of systems biology, and since I have an
interest in modeling (in biology and physiology ), I was very pleased when I
was given the opportunity to do my thesis here in the ISB group.

Adiponectin, which is a hormone released by mature
adipocyte has been shown to have an important role in the development of type-2
diabetes. However, the precise underlying mechanisms for the production and
release of such hormones in adipocytes are not fully understood. Therefore, an
ongoing project in the ISB group has been to use mathematical modeling to
describe the exocytosis of white adipocytes to predict adiponectin secretion,
making it possible to quantify the exocytosis and endocytosis rates. An article
on the subject was recently published by William Lövfors et al and in my
project I will make use of the model presented in this article. The goal is to
extend the model to also describe the experimental data for adiponectin
secretion induced through the activation of beta-adrenergic signaling pathways
upon extracellular adrenalin stimulation. Hopefully this might contribute to
creating a more complete framework for understanding the regulation of this
important metabolic hormone.

This autumn, we welcome another new student in our group: Victor Viberg

Hi, my name is Victor Viberg. I’m studying
biomedical engineering at Linköping University, currently I’m working on my
master thesis in the ISB-group at IMT.

The goal of my project is to create a
model that can explain the metabolic fluxes of a cancer cell and how it differs
from a regular healthy cell. Hopefully this new insight will help in developing
more effective treatments for cancer. The model is based on isotropic labeling
of metabolites, and it is the first time this type of data is available for a
whole human cell. My work will build on the previous work of Nicolas Sundqvist.

This autumn, we welcome another new student in our group: Thea Sandqvist

Hi!

My name is Thea and
I’m here in the ISB Group to do a project in systems biology for my 6th semester in Medicine.

My project is about insulin- and
glucose metabolism in rodents switching between chow- and high fatty based-diets. The project is based on a multi-level-multi-scale model
conducted by former ISB Group-member Niclas Berqqvist. My experimental data
comes from Karin G. Stenkula and her research group in Lund.

Besides spending time at the office I enjoy an occational pain-au-chocolat (or two or five).